Last updated: April 13, 2026

Protein Solubility Calculator

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Protein Solubility

Protein solubility is influenced by the ionic strength of the solution. At low ionic strength, solubility often increases (salting-in), while at high ionic strength, it decreases (salting-out).

log(S) = log(S₀) + K_in · √I − K_out · I
M
mg/mL
14.06
mg/mL

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